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Each subunit of the metabotropic and ionotropic receptors is encoded by a single gene [13]

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Moreover, achieving signaling bias through allosteric modulation could enhance the safety of M1-mAChR drugs, making it a key consideration in the development of M1-mAChR allosteric ligands

Structurally, the C6-C3-C6 backbone serves as the fundamental scaffold for the biological activities of flavonoids, while different subclasses, including flavones, flavonols, flavanones, and isoflavones, exhibit distinct functional characteristics due to variations in their molecular structures

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This information is provided for educational purposes only and is not intended to diagnose, treat, cure or prevent any disease.